Peter Seizer Selected Research

Cyclophilin A

1/2020	Platelet surface expression of cyclophilin A is associated with increased mortality in patients with symptomatic coronary artery disease.
11/2017	Extracellular Cyclophilin A Augments Platelet-Dependent Thrombosis and Thromboinflammation.
1/2016	Platelet-bound cyclophilin A in patients with stable coronary artery disease and acute myocardial infarction.
3/2015	Extracellular cyclophilin A activates platelets via EMMPRIN (CD147) and PI3K/Akt signaling, which promotes platelet adhesion and thrombus formation in vitro and in vivo.
1/2015	The Novel Extracellular Cyclophilin A (CyPA) - Inhibitor MM284 Reduces Myocardial Inflammation and Remodeling in a Mouse Model of Troponin I -Induced Myocarditis.
4/2014	Cyclophilin A and EMMPRIN (CD147) in cardiovascular diseases.
3/2013	EMMPRIN and its ligand cyclophilin A as novel diagnostic markers in inflammatory cardiomyopathy.
2/2013	Cyclophilin A predicts clinical outcome in patients with congestive heart failure undergoing endomyocardial biopsy.
8/2012	Intracellular cyclophilin A is an important Ca(2+) regulator in platelets and critically involved in arterial thrombus formation.
7/2012	Cyclophilin A affects inflammation, virus elimination and myocardial fibrosis in coxsackievirus B3-induced myocarditis.

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Peter Seizer Research Topics

Disease

15	Thrombosis (Thrombus) 10/2019 - 09/2006
10	Acute Coronary Syndrome 01/2018 - 09/2006
9	Inflammation (Inflammations) 10/2018 - 03/2010
7	Coronary Artery Disease (Coronary Atherosclerosis) 01/2020 - 01/2010
6	Atherosclerosis 02/2018 - 04/2008
6	Myocardial Infarction 02/2018 - 05/2008
5	Myocarditis (Carditis) 01/2020 - 07/2012
5	Heart Failure 01/2019 - 11/2009
5	Necrosis 01/2019 - 09/2006
5	Atherosclerotic Plaque (Atheroma) 12/2014 - 10/2008
4	Cardiovascular Diseases (Cardiovascular Disease) 01/2020 - 04/2014
4	Atrial Fibrillation 01/2018 - 05/2009
3	Cardiac Arrhythmias (Arrythmia) 02/2022 - 05/2012
3	Infarction (Infarctions) 01/2019 - 01/2011
3	Cardiomyopathies (Cardiomyopathy) 10/2018 - 02/2013
3	Hemorrhage 01/2018 - 12/2017
3	Fibrosis (Cirrhosis) 01/2018 - 07/2012
2	ST Elevation Myocardial Infarction 01/2019 - 06/2011
2	Non-ST Elevated Myocardial Infarction 01/2018 - 06/2011
2	Mitral Valve Insufficiency (Mitral Regurgitation) 01/2018 - 01/2016
2	Cardiogenic Shock 12/2017 - 01/2017
2	Shock 09/2016 - 01/2016
2	Ischemia 10/2012 - 01/2008
2	Neointima 10/2012 - 10/2008
2	Myocardial Ischemia (Ischemic Heart Diseases) 06/2011 - 01/2011
1	Ventricular Tachycardia 02/2022
1	Patent Foramen Ovale 10/2019
1	Cicatrix (Scar) 01/2019
1	Disease Progression 02/2018
1	Atrial Remodeling 01/2018
1	Pneumonia (Pneumonitis) 12/2017
1	Thromboinflammation 11/2017
1	Endocarditis 09/2016
1	Pathologic Constriction (Stenosis) 04/2016
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 04/2016
1	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 01/2016

Drug/Important Bio-Agent (IBA)

10	Cyclophilin AIBA 01/2020 - 07/2012
7	Basigin (Extracellular Matrix Metalloproteinase Inducer (EMMPRIN))IBA 02/2018 - 03/2010
7	Collagen ReceptorsIBA 10/2012 - 09/2006
6	Glycoproteins (Glycoprotein)IBA 06/2011 - 09/2006
4	Biomarkers (Surrogate Marker)IBA 01/2020 - 07/2008
4	platelet membrane glycoprotein VIIBA 06/2011 - 05/2009
4	TroponinIBA 05/2010 - 09/2006
3	GadoliniumIBA 01/2020 - 01/2016
3	CytokinesIBA 02/2018 - 01/2011
3	Matrix Metalloproteinases (MMPs)IBA 06/2015 - 03/2013
3	Phosphotransferases (Kinase)IBA 03/2015 - 10/2012
3	Macrophage Migration-Inhibitory FactorsIBA 12/2014 - 11/2013
3	Apolipoproteins E (ApoE)IBA 11/2013 - 10/2008
3	LigandsIBA 03/2013 - 06/2011
3	CollagenIBA 10/2012 - 10/2008
3	MB Form Creatine KinaseIBA 06/2011 - 07/2008
3	Creatine Kinase (Creatine Phosphokinase)IBA 06/2011 - 09/2006
2	Troponin IIBA 01/2015 - 06/2011
2	AntibodiesIBA 06/2011 - 01/2008
1	Neurofibromin 2 (Merlin)IBA 02/2022
1	antineoplaston A10 (A 10)IBA 01/2020
1	Messenger RNA (mRNA)IBA 01/2019
1	Complement System Proteins (Complement)IBA 10/2018
1	AnaphylatoxinsIBA 10/2018
1	Cyclophilins (Cyclophilin)IBA 02/2018
1	ChemokinesIBA 02/2018
1	Factor Xa (Coagulation Factor Xa)IBA 01/2018
1	Heparin (Liquaemin)FDA LinkGeneric 01/2018
1	2'- deoxythymidylyl- (3'- 5')- 2'- deoxyadenosine (d(AT))IBA 01/2018
1	RivaroxabanIBA 01/2018
1	MicroRNAs (MicroRNA)IBA 01/2018
1	Clopidogrel (Plavix)FDA Link 01/2018
1	TicagrelorIBA 01/2018
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2018
1	Adenosine (Adenocard)FDA LinkGeneric 01/2018
1	C-Reactive ProteinIBA 12/2017
1	Pharmaceutical PreparationsIBA 09/2016
1	CatecholaminesIBA 09/2016
1	GlucocorticoidsIBA 03/2015
1	ferric chlorideIBA 03/2015
1	EnzymesIBA 12/2014
1	Transforming Growth Factor beta (TGF-beta)IBA 12/2014
1	sphingosine kinaseIBA 11/2014
1	CeramidesIBA 01/2014
1	Fluoxetine (Prozac)FDA LinkGeneric 01/2014
1	ElementsIBA 01/2014
1	Sphingomyelin Phosphodiesterase (Sphingomyelinase)IBA 01/2014
1	Thrombin FDA Link 01/2014
1	AcidsIBA 01/2014

Therapy/Procedure

8	Therapeutics 01/2020 - 05/2008
4	Catheter Ablation 01/2018 - 05/2012
3	Heart-Assist Devices 10/2019 - 04/2016
3	Stents 05/2009 - 05/2008
2	Implantable Defibrillators (Implantable Cardioverter-Defibrillator) 02/2022 - 01/2015
2	Heart Transplantation (Grafting, Heart) 10/2018 - 02/2013
2	Surgical Instruments (Clip) 01/2018 - 01/2016
2	Extracorporeal Membrane Oxygenation 12/2017 - 01/2017
2	Patient Readmission 01/2015 - 02/2013
1	Secondary Prevention 10/2019
1	Transcatheter Aortic Valve Replacement 01/2018
1	Percutaneous Coronary Intervention 12/2017
1	Drug Therapy (Chemotherapy) 04/2016
1	Cell Transplantation 04/2016
1	Drug-Eluting Stents 04/2016